Emmy Award Wins

• Richard Mulligan, Outstanding Lead Actor in a Comedy Series, 1989, for episode “A Life in the Day”

Emmy Award Nominations

• Richard Mulligan, Outstanding Lead Actor in a Comedy Series, 1990, for episode “On the Interpretation of Dreams”
• Danny Thomas, Outstanding Guest Actor in a Comedy Series, 1991, for episode “The Mentor”
• Richard Mulligan, Oustanding Lead Actor in a Comedy Series, 1991, for episode “The Mentor”
• Kenneth Tamburri, Ritch Kenney, Jack Chisholm, Stephen A. Jones, David Heckman and John O’Brien, Outstanding Technical Direction/Camera/Video for a Series, 1991, for episode “The Last Temptation of Laverne”
• Kenneth Tamburri, Ritch Kenney, Stephen A. Jones, Chester Jackson, Dave Heckman and John O’Brien, Oustanding Technical Direction/Camera/Video for a Series, 1994, for episode “Das Boob”

Golden Globe Award Wins

• Richard Mulligan, Best Performance by an Actor in a TV Series, Comedy or Musical, 1989

Golden Globe Award Nominations

• Empty Nest, Best TV Series, Comedy or Musical, 1990
• Richard Mulligan, Best Performance by an Actor in a TV Series, Comedy or Musical, 1990 and 1991
• Park Overall, Best Supporting Actress in a Series, Mini-Series or Motion Picture Made for TV, 1991, 1992 and 1993

Viewers for Quality Television Award Wins

• Park Overall, Best Supporting Actress – Comedy, 1989, 1990 and 1991

ASCAP Film and Television Music Awards Wins

• John Bettis and George Aliceson Tipton, Top TV Series, 1990 and 1991

Young Artist Award Nominations

• Empty Nest, Best New Television Series, 1989
• Mayim Bialik, Best Young Actress Guest Starring in a Television Series, 1990, for episode “The R.N. Who Came to Dinner”
• Hayley Tyrie, Best Young Actress Guest Starring in a Television Series, 1991, for episode “Take My Mom, Please”
• Ami Foster, Best Young Actress Guest Starring in a Television Series, 1992, for episode “Fifty Million Men and a Baby”